Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.69 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29179819 | 1.00 | SCN8A (0.69) | SCN8ASCN10A | |
| SCHEMBL20644020 | 0.92 | SCN8A (0.68) | SCN8ASCN10A | |
| SCHEMBL30931237 | 0.91 | SCN8A (0.58) | SCN8ASCN10A | |
| SCHEMBL29182975 | 0.91 | SCN8A (0.58) | SCN8ASCN10A | |
| SCHEMBL29919017 | 0.90 | SCN8A (0.70) | SCN8ASCN10A | |
| SCHEMBL15561807 | 0.90 | SCN8A (0.70) | SCN8ASCN10A | |
| SCHEMBL16398006 | 0.85 | — | — | |
| SCHEMBL29918776 | 0.85 | — | — | |
| SCHEMBL20638991 | 0.84 | SCN8A (0.67) | SCN8ASCN10A | |
| SCHEMBL30530169 | 0.84 | SCN8A (0.67) | SCN8ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794919-A | N- (hydroxyalkyl (hetero) aryl) tetrahydrofurancarboxamide analogues as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2024-03-29 | — | — | CN | disclosed |