Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.58 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29182975 | 1.00 | SCN8A (0.58) | SCN8ASCN10ANR1H4PPARGPPARD | |
| SCHEMBL30853207 | 0.91 | SCN8A (0.69) | SCN8ASCN10A | |
| SCHEMBL29179819 | 0.91 | SCN8A (0.69) | SCN8ASCN10A | |
| SCHEMBL30530169 | 0.84 | SCN8A (0.67) | SCN8ASCN10A | |
| SCHEMBL20638991 | 0.84 | SCN8A (0.67) | SCN8ASCN10A | |
| SCHEMBL15931097 | 0.83 | SCN8A (0.60) | SCN8ASCN10A | |
| SCHEMBL20644020 | 0.83 | SCN8A (0.68) | SCN8ASCN10A | |
| SCHEMBL15561737 | 0.82 | — | — | |
| SCHEMBL13852934 | 0.80 | SCN8A (0.56) | SCN8ASCN10A | |
| SCHEMBL13852936 | 0.80 | SCN8A (0.56) | SCN8ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794920-A | N- (hydroxyalkyl (hetero) aryl) tetrahydrofurancarboxamides as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2024-03-29 | — | — | CN | disclosed |