Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 4/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31341692 | 0.81 | CHRM2 (0.48) | CHRM2CHRM1CHRM3NR1H2PREP | |
| SCHEMBL30853294 | 0.77 | CHRM2 (0.54) | CHRM2CHRM1CHRM3NR1H2PREP | |
| SCHEMBL1206712 | 0.76 | USP2 (0.46) | EPHX2 | |
| SCHEMBL24762766 | 0.73 | CHRM2 (0.59) | CHRM2CHRM1CHRM3NR1H2PREP | |
| SCHEMBL14410734 | 0.73 | CHRM2 (0.59) | CHRM2CHRM1CHRM3NR1H2PREP | |
| SCHEMBL25896209 | 0.73 | CHRM2 (0.59) | CHRM2CHRM1CHRM3NR1H2PREP | |
| SCHEMBL402018 | 0.73 | CHRM2 (0.59) | CHRM2CHRM1CHRM3NR1H2PREP | |
| SCHEMBL18713026 | 0.73 | CHRM2 (0.59) | CHRM2CHRM1CHRM3NR1H2PREP | |
| SCHEMBL3935909 | 0.73 | CHRM2 (0.59) | CHRM2CHRM1CHRM3NR1H2PREP | |
| SCHEMBL30853292 | 0.73 | CHRM2 (0.51) | CHRM2CHRM1CHRM3NR1H2PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574201-B | Arylamine compound, pharmaceutical composition containing arylamine compound, and preparation method and application of arylamine compound | 四川科伦博泰生物医药股份有限公司 | 2024-04-19 | — | — | CN | disclosed |