Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | PREP | P48147 | 4/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22181639 | 0.92 | CHRM2 (0.55) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL30853288 | 0.91 | CHRM2 (0.51) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL30853292 | 0.86 | CHRM2 (0.51) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL15725772 | 0.85 | CHRM2 (0.46) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL26361913 | 0.84 | CHRM2 (0.64) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL26924922 | 0.82 | CHRM2 (0.48) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL25343472 | 0.80 | CHRM2 (0.51) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL16446458 | 0.79 | CHRNB2 (0.34) | — | |
| SCHEMBL24670611 | 0.78 | HRH3 (0.40) | CHRM2CHRM1CHRM3NR1H2HPGD | |
| SCHEMBL30853293 | 0.77 | CHRM2 (0.46) | CHRM2CHRM1CHRM3PREPNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574201-B | Arylamine compound, pharmaceutical composition containing arylamine compound, and preparation method and application of arylamine compound | 四川科伦博泰生物医药股份有限公司 | 2024-04-19 | — | — | CN | disclosed |