Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31430856 | 0.72 | KDM4E (0.53) | KDM4EALDH1A1ATMPARP1L3MBTL1 | |
| SCHEMBL5201337 | 0.69 | KDM4E (0.72) | KDM4EALDH1A1ATMPARP1PIM1 | |
| SCHEMBL31609554 | 0.69 | KDM4E (0.72) | KDM4EALDH1A1ATMPARP1PIM1 | |
| SCHEMBL30853351 | 0.69 | PARP1 (0.43) | KDM4EALDH1A1PARP1 | |
| SCHEMBL637079 | 0.68 | IKBKB (0.50) | KDM4EALDH1A1ATMPARP1PIM1 | |
| SCHEMBL30853320 | 0.68 | BTK (0.45) | KDM4EALDH1A1ATMPIM1PIM3 | |
| SCHEMBL31206040 | 0.67 | PDPK1 (0.38) | KDM4EALDH1A1ATMPARP1 | |
| SCHEMBL1210894 | 0.66 | GAA (0.50) | ALDH1A1ATMPIM1PIM3 | |
| SCHEMBL918559 | 0.63 | — | — | |
| SCHEMBL164592 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |