Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | ATM | Q13315 | 2/20 | 0.65 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201337 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1ATMPIM1PIM3 | |
| SCHEMBL2676355 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1ATMPARP1GPR84 | |
| SCHEMBL10372680 | 0.81 | KDM4E (0.72) | KDM4EALDH1A1ATMPARP1KMT2A | |
| SCHEMBL2922430 | 0.81 | KDM4E (0.72) | KDM4EALDH1A1ATMPARP1KMT2A | |
| Lithium Ion SCHEMBL23216369 | 0.79 | KDM4E (0.70) | KDM4EALDH1A1ATMPARP1KMT2A | |
| Lithium Ion SCHEMBL29745661 | 0.79 | KDM4E (0.70) | KDM4EALDH1A1ATMPARP1KMT2A | |
| SCHEMBL29544426 | 0.78 | ALDH1A1 (1.00) | ALDH1A1ATMPIM1PIM3KMT2A | |
| SCHEMBL117198 | 0.78 | ALDH1A1 (1.00) | ALDH1A1ATMPIM1PIM3KMT2A | |
| SCHEMBL27785298 | 0.78 | ALDH1A1 (1.00) | ALDH1A1ATMPIM1PIM3KMT2A | |
| SCHEMBL2521184 | 0.78 | PARP1 (0.58) | KDM4EALDH1A1ATMPARP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179087-A1 | COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS | Immunophage Biotech (Shanghai) Co., Ltd. (CN) | 2025-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179087-A1 | COMPOUNDS AND THEIR USES AS LPAR5 ANTAGONISTS | LPAR5, LPAR3, LPAR2 | KDM4E 3010/4885ALDH1A1 2592/4885ATM 4058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.