Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 12/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1201914 | 1.00 | ALDH1A1 (0.49) | ALDH1A1HPGDNR1H2KDM4ENPSR1 | |
| SCHEMBL30023124 | 0.87 | NR1H2 (0.41) | ALDH1A1HPGDNR1H2KDM4ECA12 | |
| SCHEMBL23956770 | 0.84 | USP30 (0.38) | NR1H2 | |
| SCHEMBL19964584 | 0.84 | USP30 (0.40) | ALDH1A1HPGDNR1H2 | |
| SCHEMBL30396372 | 0.84 | USP30 (0.38) | NR1H2 | |
| SCHEMBL18537881 | 0.83 | NR1H2 (0.53) | NR1H2CA12CA9NR1H3 | |
| SCHEMBL30023415 | 0.81 | DTYMK (0.41) | ALDH1A1HPGDNR1H2KDM4E | |
| SCHEMBL23930164 | 0.81 | DTYMK (0.41) | ALDH1A1HPGDNR1H2KDM4E | |
| SCHEMBL29631893 | 0.77 | NR1H2 (0.40) | NR1H2CA12CA9NR1H3 | |
| SCHEMBL19013553 | 0.77 | NR1H2 (0.40) | NR1H2CA12CA9NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397822-B | CBP/EP300 inhibitors and uses thereof | 南京药石科技股份有限公司 | 2024-04-16 | — | — | CN | disclosed |