Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329238 | 0.78 | MAPT (1.00) | TDP1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL11318226 | 0.78 | MAPT (1.00) | TDP1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL16556 | 0.78 | MAPT (1.00) | TDP1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL205992 | 0.78 | MAPT (1.00) | TDP1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL11329226 | 0.78 | MAPT (1.00) | TDP1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL11329248 | 0.78 | MAPT (1.00) | TDP1MAPTMEN1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL11648849 | 0.75 | TDP1 (0.93) | TDP1MAPTMEN1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL11648851 | 0.75 | TDP1 (0.93) | TDP1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL141822 | 0.74 | CYP17A1 (0.43) | MAPTADRA2AADRA2BADRA2CKDM4E | |
| SCHEMBL141823 | 0.74 | CYP17A1 (0.43) | MAPTADRA2AADRA2BADRA2CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118047944-A | Preparation method and application of AGT inhibitor conjugate targeting glucose transporter and low-oxygen environment | 北京工业大学 | 2024-05-17 | — | — | CN | claimed |
| CN-118047944-A | Preparation method and application of AGT inhibitor conjugate targeting glucose transporter and low-oxygen environment | 北京工业大学 | 2024-05-17 | — | — | CN | disclosed |