SCHEMBL141822

SCHEMBL141822

c1cc(/N=N/c2ccsc2)ccn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.43
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
ADRA2A P08913 2/20 0.42
ADRA2B P18089 2/20 0.42
ADRA2C P18825 2/20 0.42
CCNT1 O60563 2/20 0.38
CDK1 P06493 2/20 0.38
CDK4 P11802 2/20 0.38
CCNB1 P14635 2/20 0.38
CCND1 P24385 2/20 0.38
CCNE1 P24864 2/20 0.38
CDK2 P24941 2/20 0.38
CDK9 P50750 2/20 0.38
CDK7 P50613 1/20 0.38
CCNH P51946 1/20 0.38
MAPT P10636 2/20 0.36
LMNA P02545 1/20 0.36
PLG P00747 1/20 0.35
CYP2A6 P11509 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141823 1.00 CYP17A1 (0.43) CYP17A1CYP11B1CYP11B2ADRA2AADRA2B
SCHEMBL139295 0.78 CCNT1 (0.50) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL106526 0.78 CCNT1 (0.50) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL30853512 0.74 TDP1 (0.61) ADRA2AADRA2BADRA2CMAPTCYP3A4
SCHEMBL7048557 0.70
SCHEMBL3291145 0.69 ALDH1A1 (0.67) ADRA2BADRA2CCCNT1CDK1CDK4
SCHEMBL3291148 0.69 ALDH1A1 (0.67) ADRA2BADRA2CCCNT1CDK1CDK4
SCHEMBL1356085 0.67 CYP17A1 (0.70) CYP17A1CYP11B1CYP11B2MAPTLMNA
SCHEMBL4349980 0.65 NPC1 (0.58) CYP17A1CYP11B1CYP11B2CCNT1CDK1
SCHEMBL146201 0.65 CCNT1 (0.41) CCNT1CDK1CDK4CCNB1CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2433131-B1 Particles for long wavelength SERS, method of manufacture and method for tagging a material SICPA HOLDING SA (CH) 2016-07-06 EP claimed
US-9239327-B2 Particles comprising hollow surface-enhanced spectroscopy (SES)-active core for long wavelength SERS SICPA HOLDING SA (CH) 2016-01-19 US claimed
EP-2433131-A1 PARTICLES AND METHODS FOR LONG WAVELENGTH SERS Cabot Security Materials Inc. (US) 2012-03-28 EP claimed
US-20120057165-A1 Particles and Methods for Long Wavelength SERS CABOT SECURITY MATERIALS INC. (US) 2012-03-08 US claimed
WO-2010135354-A1 PARTICLES AND METHODS FOR LONG WAVELENGTH SERS OXONICA MATERIALS INC. (US) 2010-11-25 WO claimed
EP-2433131-B1 Particles for long wavelength SERS, method of manufacture and method for tagging a material SICPA HOLDING SA (CH) 2016-07-06 EP disclosed
US-9239327-B2 Particles comprising hollow surface-enhanced spectroscopy (SES)-active core for long wavelength SERS SICPA HOLDING SA (CH) 2016-01-19 US disclosed
EP-2433131-A1 PARTICLES AND METHODS FOR LONG WAVELENGTH SERS Cabot Security Materials Inc. (US) 2012-03-28 EP disclosed
US-20120057165-A1 Particles and Methods for Long Wavelength SERS CABOT SECURITY MATERIALS INC. (US) 2012-03-08 US disclosed
WO-2010135354-A1 PARTICLES AND METHODS FOR LONG WAVELENGTH SERS OXONICA MATERIALS INC. (US) 2010-11-25 WO disclosed