SCHEMBL3085366

SCHEMBL3085366

O=C(c1ccc(Oc2ccc(C(=O)O)c(C(=O)O)c2)cc1)c1ccccc1Oc1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.76
CDC25B P30305 2/20 0.55
CDC25A P30304 1/20 0.55
HSD17B10 Q99714 1/20 0.55
HPSE Q9Y251 2/20 0.54
PYGL P06737 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
GALK1 P51570 1/20 0.52
CASP6 P55212 1/20 0.52
MCL1 Q07820 1/20 0.52
PLEC Q15149 1/20 0.52
SRD5A2 P31213 2/20 0.51
PYGM P11217 4/20 0.51
KDM4E B2RXH2 2/20 0.50
AKR1C3 P42330 1/20 0.49
APEX1 P27695 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
ATM Q13315 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4472633 0.94 POLB (0.70) POLBCDC25BCDC25AHSD17B10HPSE
SCHEMBL3073043 0.90 POLB (0.62) POLBCDC25BCDC25AHSD17B10HPSE
SCHEMBL3074650 0.89 POLB (0.63) POLBCDC25BCDC25AHSD17B10HPSE
SCHEMBL5963366 0.86 POLB (1.00) POLBCDC25BCDC25AHSD17B10HPSE
SCHEMBL10448654 0.86 SRD5A2 (0.62) POLBHPSEMCL1SRD5A2
SCHEMBL28634306 0.86 POLB (0.61) POLBHPSEPYGLTDP1GALK1
SCHEMBL425842 0.85 POLB (0.70) POLBCDC25BCDC25AHSD17B10HPSE
SCHEMBL29405908 0.85 POLB (0.90) POLBCDC25BCDC25AHSD17B10HPSE
SCHEMBL423130 0.85 POLB (0.90) POLBCDC25BCDC25AHSD17B10HPSE
SCHEMBL7057386 0.83 POLB (0.63) POLBCDC25BCDC25AHSD17B10HPSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100226016-A1 LIGHT-SHIELDING FILM NIPPON SHOKUBAI CO., LTD. (JP) 2010-09-09 US disclosed
EP-2183622-A1 LIGHT-SHIELDING FILM Nippon Shokubai Co., Ltd. (JP) 2010-05-12 EP disclosed
US-20090280339-A1 POLYIMIDE FILM, POLYIMIDE METAL LAMINATE USING SAME, AND METHOD FOR MANUFACTURING SAME MITSUI CHEMICALS ,INC. (JP) 2009-11-12 US disclosed
WO-2009014264-A1 LIGHT-SHIELDING FILM NIPPON SHOKUBAI CO., LTD. (JP) 2009-01-29 WO disclosed
US-20080299402-A1 Polyimide film, polyimide metal laminate and process for producing the same MITSUI CHEMICALS, INC. (JP) 2008-12-04 US disclosed
US-20040096679-A1 Metal laminate MITSUI CHEMICALS, INC. (JP) 2004-05-20 US disclosed
EP-1420048-A2 Metal laminate Mitsui Chemicals, Inc. (JP) 2004-05-19 EP disclosed