SCHEMBL425842

SCHEMBL425842

O=C(c1ccc(Oc2ccc(C(=O)O)c(C(=O)O)c2)cc1)c1ccc(Oc2cccc(C(=O)O)c2C(=O)O)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.70
HPSE Q9Y251 2/20 0.54
TDP1 Q9NUW8 5/20 0.49
GALK1 P51570 1/20 0.49
CASP6 P55212 1/20 0.49
MCL1 Q07820 1/20 0.49
PLEC Q15149 1/20 0.49
CDC25A P30304 1/20 0.48
CDC25B P30305 1/20 0.48
HSD17B10 Q99714 1/20 0.48
SRD5A2 P31213 1/20 0.48
PYGM P11217 5/20 0.46
PYGL P06737 4/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
APEX1 P27695 1/20 0.45
CTDSP1 Q9GZU7 1/20 0.45
DUSP3 P51452 1/20 0.45
PTPN5 P54829 1/20 0.45
PTPN11 Q06124 1/20 0.45
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL422032 0.93 POLB (0.57) POLBHPSETDP1GALK1CASP6
SCHEMBL716921 0.90 PYGL (0.53) POLBHPSETDP1GALK1CASP6
SCHEMBL29404149 0.90 PYGL (0.53) POLBHPSETDP1GALK1CASP6
SCHEMBL425732 0.90 SRD5A2 (0.53) POLBHPSECDC25ACDC25BHSD17B10
SCHEMBL3417323 0.89 TDP1 (0.54) POLBHPSETDP1GALK1CASP6
SCHEMBL420308 0.86 POLB (0.50) POLBHPSETDP1GALK1CASP6
SCHEMBL3085366 0.85 POLB (0.76) POLBHPSETDP1GALK1CASP6
SCHEMBL421351 0.85 POLB (0.59) POLBHPSETDP1GALK1CASP6
SCHEMBL425841 0.84 CTNNB1 (0.49) POLBTDP1HSD17B10SRD5A2L3MBTL1
SCHEMBL29658106 0.84 CTNNB1 (0.49) POLBTDP1HSD17B10SRD5A2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117806123-B Chemical amplification type negative photosensitive polyimide composition and application thereof 明士(北京)新材料开发有限公司 2024-05-31 CN claimed
US-11905381-B2 Polyimide microparticles XEROX CORPORATION (US) 2024-02-20 US claimed
US-20220363843-A1 POLYIMIDE MICROPARTICLES XEROX CORPORATION (US) 2022-11-17 US claimed
EP-4089136-A1 POLYIMIDE MICROPARTICLES Xerox Corporation (US) 2022-11-16 EP claimed
CN-115322398-A Polyimide fine particles 施乐公司 2022-11-11 CN claimed
CN-102015833-B There is polyetherimide and the polyetherimide sulfone blends of automotive illumination applications SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2015-12-16 CN claimed
US-9161440-B2 Articles comprising a polyimide solvent cast film having a low coefficient of thermal expansion and method of manufacture thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-10-13 US claimed
EP-2032634-B1 POLYIMIDE SOLVENT CAST FILMS HAVING LOW COEFFICIENT OF THERMAL EXPANSION AND METHOD OF MANUFACTURE THEREOF GEN ELECTRIC (US) 2015-05-13 EP claimed
EP-2041209-B1 ARTICLES COMPRISING A POLYIMIDE SOLVENT CAST FILM HAVING A LOW COEFFICIENT OF THERMAL EXPANSION AND METHOD OF MANUFACTURE THEREOF SABIC INNOVATIVE PLASTICS IP (NL) 2014-11-26 EP claimed
EP-2081977-B1 ARTICLES COMPRISING A POLYIMIDE SOLVENT CAST FILM HAVING A LOW COEFFICIENT OF THERMAL EXPANSION AND METHOD OF MANUFACTURE THEREOF SABIC INNOVATIVE PLASTICS IP (NL) 2013-12-11 EP claimed
US-20030225221-A1 High performance thermoplastic compositions with improved melt flow properties SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2003-12-04 US claimed
US-20030216506-A1 Method of manufacture of polyester molding compositions and articles produced therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2003-11-20 US claimed
WO-2003080709-A1 PREPARATION OF POLYIMIDE POLYMERS GENERAL ELECTRIC COMPANY (US) 2003-10-02 WO claimed
US-20030181626-A1 Preparation of polyimide polymers SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2003-09-25 US claimed
US-20030125478-A1 HIGH PERFORMANCE THERMOPLASTIC COMPOSITIONS WITH IMPROVED MELT FLOW PROPERTIES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2003-07-03 US claimed
EP-1318174-A1 Method of manufacture of polyester molding compositions and articles produced therefrom GENERAL ELECTRIC COMPANY (US) 2003-06-11 EP claimed
WO-2003040213-A1 HIGH MOLECULAR WEIGHT POLY(IMIDE)S AND METHODS OF SYNTHESIS THEREOF GENERAL ELECTRIC COMPANY (US) 2003-05-15 WO claimed
EP-1287076-A2 HIGH PERFORMANCE THERMOPLASTIC COMPOSITIONS WITH IMPROVED MELT FLOW PROPERTIES GENERAL ELECTRIC COMPANY (US) 2003-03-05 EP claimed
US-6500904-B1 FROM THE COUPLING OF LOWER MOLECULAR WEIGHT FUNCTIONALIZED PRECURSOR POLYIMIDES GENERAL ELECTRIC COMPANY 2002-12-31 US claimed
WO-2001096477-A2 HIGH PERFORMANCE THERMOPLASTIC COMPOSITIONS WITH IMPROVED MELT FLOW PROPERTIES GENERAL ELECTRIC COMPANY (US) 2001-12-20 WO claimed