SCHEMBL308543

SCHEMBL308543

[CH2]C=CCC(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL308542 1.00
SCHEMBL28168136 0.79 CYP2D6 (1.00)
SCHEMBL3134391 0.79 CYP2D6 (1.00)
SCHEMBL190067 0.79 CYP2D6 (1.00)
SCHEMBL213024 0.79 CYP2D6 (1.00)
Ammonia Solution, Strong SCHEMBL25317379 0.76 CYP2D6 (0.92)
Hydrochloric Acid SCHEMBL10880042 0.76 CYP2D6 (0.92)
Ammonia Solution, Strong SCHEMBL25317376 0.76 CYP2D6 (0.92)
SCHEMBL4078133 0.73 CYP2D6 (0.73)
SCHEMBL4970454 0.73 CYP2D6 (0.73)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7105523-B2 Carbamate-substituted pyrazolopyridine-derivatives BAYER AKTIENGESELISCHAFT (DE) 2006-09-12 US claimed
EP-1339717-B1 NOVEL CARBAMATE-SUBSTITUTED PYRAZOLOPYRIDINE DERIVATIVES BAYER HEALTHCARE AG (DE) 2005-02-09 EP claimed
US-20040082596-A1 Novel carbamate-substituted pyrazolopyridine derivatives BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2004-04-29 US claimed
EP-1339717-A1 NOVEL CARBAMATE-SUBSTITUTED PYRAZOLOPYRIDINE DERIVATIVES Bayer Aktiengesellschaft (DE) 2003-09-03 EP claimed
WO-2002042300-A1 NOVEL CARBAMATE-SUBSTITUTED PYRAZOLOPYRIDINE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2002-05-30 WO claimed
EP-0832082-B1 N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS ASTRAZENECA AB (SE) 2001-11-21 EP claimed
EP-0832082-A1 N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS ZENECA LIMITED (GB) 1998-04-01 EP claimed
US-5668137-A N-heterocyclic sulfonamides having endothelin receptor activity ZENECA LTD. (GB) 1997-09-16 US claimed
EP-0749964-A1 N-Heterocyclyl biphenyl sulfonamides ZENECA LIMITED (GB) 1996-12-27 EP claimed
WO-1996040681-A1 N-HETEROARYL-PYRIDINESULFONAMIDE DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS ZENECA LIMITED (GB) 1996-12-19 WO claimed
US-20240199821-A1 WATER-ABSORBING RESIN NAGASE VIITA CO., LTD. (JP) 2024-06-20 US disclosed
WO-2024029246-A1 ABSORBENT ARTICLE 長瀬産業株式会社 2024-02-08 WO disclosed
EP-4317193-A1 METHOD FOR PRODUCING WATER-SOLUBLE POLYMER AND METHOD FOR PRODUCING WATER-ABSORBING RESIN Nagase & Co., Ltd. (JP) 2024-02-07 EP disclosed
EP-4317194-A1 WATER-ABSORBING RESIN Nagase & Co., Ltd. (JP) 2024-02-07 EP disclosed
CN-117120480-A Method for producing water-soluble polymer and method for producing water-absorbent resin 长濑产业株式会社 2023-11-24 CN disclosed
US-4584290-A MICROBIOCIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-04-22 US disclosed
EP-0154354-A2 New cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-09-11 EP disclosed
EP-0145906-A2 Cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-06-26 EP disclosed
EP-0133678-A2 New cephem compounds, processes for preparation thereof and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-03-06 EP disclosed
EP-0111281-A2 New cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-06-20 EP disclosed