SCHEMBL30854928

SCHEMBL30854928

COCCc1nc2c(N)nc3ccccc3c2n1CCOCCN(C)S(C)(=O)=O

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.54
TLR8 Q9NR97 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483620 1.00 TLR7 (0.54) TLR7TLR8
SCHEMBL5119677 0.91 TLR8 (0.51) TLR7TLR8
SCHEMBL1890833 0.89 TLR8 (0.59) TLR7TLR8
SCHEMBL31006041 0.87 TLR8 (0.55) TLR7TLR8
SCHEMBL5113123 0.85 TLR7 (0.62) TLR7TLR8
SCHEMBL6031026 0.84 TLR7 (0.57) TLR7TLR8
SCHEMBL1043163 0.84 TLR8 (0.74) TLR7TLR8
SCHEMBL5736958 0.83 TLR7 (0.56) TLR7TLR8
SCHEMBL4331154 0.82 TLR7 (0.56) TLR7TLR8
SCHEMBL4336407 0.82 TLR7 (0.55) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240417738-A1 IMMUNOTHERAPIES FOR THE TREATMENT OF CANCER OHIO STATE INNOVATION FOUNDATION 2024-12-19 US disclosed
US-20240033348-A1 METHODS AND COMPOSITIONS FOR ADAPTIVE IMMUNE MODULATION Pulmotect, Inc. 2024-02-01 US disclosed