Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24714780 | 1.00 | ENPP1 (0.34) | ENPP1BRD4NTRK1GRIA1ADCY10 | |
| SCHEMBL24714366 | 0.90 | — | — | |
| SCHEMBL30854933 | 0.85 | NTRK1 (0.34) | NTRK1ALKBH1 | |
| SCHEMBL24714783 | 0.85 | NTRK1 (0.34) | NTRK1ALKBH1 | |
| SCHEMBL24714781 | 0.83 | ALKBH1 (0.32) | ALKBH1TGFBR1MAPK14 | |
| SCHEMBL30854937 | 0.83 | ALKBH1 (0.32) | ALKBH1TGFBR1MAPK14 | |
| SCHEMBL22732867 | 0.82 | HPGD (0.33) | BRD4NTRK1ADCY10ALDH1A1KDM4E | |
| SCHEMBL24714970 | 0.82 | GRIA1 (0.38) | BRD4GRIA1ADCY10KDM4EKDM4C | |
| SCHEMBL30854939 | 0.82 | GRIA1 (0.38) | BRD4GRIA1ADCY10KDM4EKDM4C | |
| SCHEMBL24714365 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957228-A | SGC stimulators | 帝善多制药公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117915917-A | CNS disease treatment using sGC stimulators | 帝善多制药公司 | 2024-04-19 | — | — | CN | disclosed |