Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 3/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29334347 | 1.00 | GPR119 (0.38) | GPR119EGLN2MEN1KMT2AGRM5 | |
| SCHEMBL14839868 | 0.84 | HRH2 (0.39) | GPR119EGLN2USP30NR1H2 | |
| SCHEMBL29334339 | 0.84 | GPR119 (0.38) | GPR119EGLN2CETP | |
| SCHEMBL14840026 | 0.83 | GPR119 (0.46) | GPR119EGLN2CETP | |
| SCHEMBL31224635 | 0.80 | HSP90AA1 (0.36) | MEN1KMT2ASTSUSP30ESR2 | |
| SCHEMBL29334072 | 0.78 | USP30 (0.38) | MEN1KMT2ASTSUSP30 | |
| SCHEMBL29334081 | 0.77 | STS (0.33) | MEN1KMT2ASTSUSP30ESR2 | |
| SCHEMBL29334170 | 0.76 | GPR119 (0.35) | GPR119MEN1KMT2AUSP30NR1H2 | |
| SCHEMBL30855145 | 0.76 | GPR119 (0.35) | GPR119MEN1KMT2AUSP30NR1H2 | |
| SCHEMBL14839844 | 0.74 | CKS1B (0.43) | GPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594308-A1 | N-ACRYLOYLMORPHOLINE DERIVATIVES AS KEAP1 MODULATORS AND USES THEREOF | Vividion Therapeutics, Inc. (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073587-A1 | N-ACRYLOYLMORPHOLINE DERIVATIVES AS KEAP1 MODULATORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |