SCHEMBL30855271

SCHEMBL30855271

CC(C)(C)OC(=O)N[C@H]1CC[C@H](CCN2CCN(c3ccc(Cl)cc3)CC2)CC1

nearest known ligand 0.71

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 10/20 0.71
DRD3 P35462 6/20 0.71
DRD4 P21917 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3108407 0.84 CNR1 (0.55) DRD2DRD3
SCHEMBL231216 0.84 DRD2 (0.63) DRD2DRD3
SCHEMBL230259 0.84 DRD2 (0.63) DRD2DRD3
SCHEMBL30855312 0.83 DRD2 (0.69) DRD2DRD3DRD4
SCHEMBL4087769 0.83 DRD2 (1.00) DRD2DRD3DRD4
SCHEMBL31278308 0.83 DRD2 (1.00) DRD2DRD3DRD4
SCHEMBL1318485 0.83 DRD2 (1.00) DRD2DRD3DRD4
SCHEMBL29502084 0.83 DRD2 (1.00) DRD2DRD3DRD4
SCHEMBL14347013 0.82 DRD2 (0.70) DRD2DRD3
SCHEMBL13630397 0.82 DRD2 (0.64) DRD2DRD3DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4594294-A1 DOPAMINE D3/D2 RECEPTOR PARTIAL AGONISTS FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS The United States of America, as represented by the Secretary, Department of Health and Human Services (US) 2025-08-06 EP disclosed
WO-2024072930-A1 DOPAMINE D3/D2 RECEPTOR PARTIAL AGONISTS FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2024-04-04 WO disclosed