Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 1.00 |
| ▸ | DRD3 | P35462 | 16/20 | 1.00 |
| ▸ | HTR2A | P28223 | 7/20 | 1.00 |
| ▸ | DRD4 | P21917 | 5/20 | 1.00 |
| ▸ | HTR1A | P08908 | 4/20 | 1.00 |
| ▸ | HTR2C | P28335 | 4/20 | 1.00 |
| ▸ | HTR2B | P41595 | 4/20 | 1.00 |
| ▸ | DRD1 | P21728 | 2/20 | 0.84 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | DRD5 | P21918 | 1/20 | 0.62 |
| ▸ | HTR7 | P34969 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30855276 | 0.91 | DRD2 (1.00) | DRD2DRD3HTR2ADRD4HTR1A | |
| SCHEMBL29904302 | 0.87 | DRD2 (0.78) | DRD2DRD3HTR2ADRD4HTR1A | |
| SCHEMBL29904305 | 0.87 | DRD2 (0.78) | DRD2DRD3HTR2ADRD4HTR1A | |
| SCHEMBL23331609 | 0.87 | DRD2 (0.78) | DRD2DRD3HTR2ADRD4HTR1A | |
| SCHEMBL25106927 | 0.87 | DRD2 (0.78) | DRD2DRD3HTR2ADRD4HTR1A | |
| SCHEMBL23331418 | 0.87 | DRD2 (0.78) | DRD2DRD3HTR2ADRD4HTR1A | |
| SCHEMBL3091220 | 0.85 | DRD3 (0.73) | DRD2DRD3HTR2ADRD4HTR1A | |
| SCHEMBL12478132 | 0.84 | DRD2 (1.00) | DRD2DRD3HTR2ADRD4HTR1A | |
| SCHEMBL229035 | 0.84 | DRD3 (0.72) | DRD2DRD3HTR2ADRD4HTR1A | |
| SCHEMBL229638 | 0.84 | DRD3 (0.72) | DRD2DRD3HTR2ADRD4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594294-A1 | DOPAMINE D3/D2 RECEPTOR PARTIAL AGONISTS FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS | The United States of America, as represented by the Secretary, Department of Health and Human Services (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024072930-A1 | DOPAMINE D3/D2 RECEPTOR PARTIAL AGONISTS FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-04-04 | — | — | WO | disclosed |