Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 11/20 | 0.51 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30855656 | 0.93 | TGFBR1 (0.46) | TGFBR1MAP3K20ROCK2PIM1GSK3B | |
| SCHEMBL30855629 | 0.85 | TGFBR1 (0.45) | TGFBR1ROCK2PIM1GSK3BMAPK14 | |
| SCHEMBL4860838 | 0.83 | TGFBR1 (0.48) | TGFBR1MAP3K20ROCK2PIM1GSK3B | |
| SCHEMBL4860181 | 0.83 | TGFBR1 (0.60) | TGFBR1ROCK2PIM1GSK3BMAPK14 | |
| SCHEMBL4865043 | 0.81 | TGFBR1 (0.59) | TGFBR1MAPK14 | |
| SCHEMBL4860883 | 0.81 | TGFBR1 (0.43) | TGFBR1MAP3K20ROCK2PIM1GSK3B | |
| SCHEMBL30855685 | 0.81 | TGFBR1 (0.46) | TGFBR1ROCK2PIM1GSK3BKLK7 | |
| SCHEMBL30182752 | 0.81 | TGFBR1 (0.45) | TGFBR1ROCK2PIM1GSK3BKLK7 | |
| SCHEMBL4866801 | 0.81 | TGFBR1 (0.42) | TGFBR1MAP3K20ROCK2PIM1GSK3B | |
| SCHEMBL30855647 | 0.80 | TGFBR1 (0.47) | TGFBR1ROCK2PIM1GSK3BKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881669-A | Condensed ring heteroaryl compounds and uses thereof | 比西切姆有限公司 | 2024-04-12 | — | — | CN | disclosed |