Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6125360 | 0.85 | HPGD (0.68) | MAPTALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL3085306 | 0.84 | MAPT (0.51) | MAPTALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL1397512 | 0.84 | ALDH1A1 (0.71) | MAPTALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL1397520 | 0.84 | HPGD (0.68) | MAPTALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL17195413 | 0.83 | MAPT (0.68) | MAPTALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL15384274 | 0.83 | ALDH1A1 (0.58) | MAPTALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL4524615 | 0.83 | ALDH1A1 (0.58) | MAPTALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL4433893 | 0.82 | KDM4E (0.77) | MAPTALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL4963219 | 0.82 | ALDH1A1 (0.62) | MAPTALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL28325509 | 0.82 | HTT (0.71) | MAPTALDH1A1HPGDTSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667236-B | 1, 5-Dihydro-2, 4-benzodiazepine-3-one derivative and application thereof | 江苏恩华药业股份有限公司 | 2024-04-26 | — | — | CN | disclosed |