Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 9/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 9/20 | 0.50 |
| ▸ | HRH1 | P35367 | 5/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23761234 | 1.00 | CARM1 (0.50) | CARM1PRMT1HRH1SLC6A2SLC6A4 | |
| SCHEMBL29786357 | 0.92 | CARM1 (0.58) | CARM1PRMT1HRH1SLC6A2SLC6A4 | |
| SCHEMBL6492804 | 0.92 | CARM1 (0.58) | CARM1PRMT1HRH1SLC6A2SLC6A4 | |
| SCHEMBL23004969 | 0.92 | CARM1 (0.55) | CARM1PRMT1HRH1SLC6A2SLC6A4 | |
| SCHEMBL29786600 | 0.91 | CARM1 (0.61) | CARM1PRMT1HRH1SLC6A2SLC6A4 | |
| SCHEMBL20472407 | 0.91 | CARM1 (0.61) | CARM1PRMT1HRH1SLC6A2SLC6A4 | |
| SCHEMBL16814992 | 0.88 | KAT2B (0.49) | CARM1PRMT1HRH1SLC6A2SLC6A4 | |
| SCHEMBL29786402 | 0.88 | KAT2B (0.49) | CARM1PRMT1HRH1SLC6A2SLC6A4 | |
| SCHEMBL3289933 | 0.85 | HRH1 (0.57) | CARM1PRMT1HRH1SLC6A2SLC6A3 | |
| SCHEMBL29786608 | 0.85 | MCHR1 (0.50) | CARM1PRMT1HRH1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667236-B | 1, 5-Dihydro-2, 4-benzodiazepine-3-one derivative and application thereof | 江苏恩华药业股份有限公司 | 2024-04-26 | — | — | CN | disclosed |