Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 9/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 9/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 3/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492804 | 1.00 | CARM1 (0.58) | CARM1PRMT1CSNK2A1HRH1MCHR1 | |
| SCHEMBL29786600 | 0.98 | CARM1 (0.61) | CARM1PRMT1CSNK2A1HRH1MCHR1 | |
| SCHEMBL20472407 | 0.98 | CARM1 (0.61) | CARM1PRMT1CSNK2A1HRH1MCHR1 | |
| SCHEMBL23004969 | 0.96 | CARM1 (0.55) | CARM1PRMT1CSNK2A1HRH1MCHR1 | |
| SCHEMBL30856498 | 0.92 | CARM1 (0.50) | CARM1PRMT1CSNK2A1HRH1SLC6A2 | |
| SCHEMBL23761234 | 0.92 | CARM1 (0.50) | CARM1PRMT1CSNK2A1HRH1SLC6A2 | |
| SCHEMBL34462788 | 0.86 | CARM1 (0.59) | CARM1PRMT1CSNK2A1HRH1MCHR1 | |
| SCHEMBL29786402 | 0.84 | KAT2B (0.49) | CARM1PRMT1CSNK2A1HRH1SLC6A2 | |
| SCHEMBL16814992 | 0.84 | KAT2B (0.49) | CARM1PRMT1CSNK2A1HRH1SLC6A2 | |
| SCHEMBL21486437 | 0.83 | HRH1 (0.53) | CARM1PRMT1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111566103-B | Aminoimidazopyrazines as kinase inhibitors | 百时美施贵宝公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-110520423-B | Aminotriazolopyridines as kinase inhibitors | 百时美施贵宝公司 | 2022-08-23 | — | — | CN | disclosed |