Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3026628 | 0.84 | USP2 (0.41) | USP2SMN1; SMN2NR1H2MEN1ALDH1A1 | |
| SCHEMBL17869750 | 0.82 | USP2 (0.43) | USP2SMN1; SMN2NR1H2MEN1ALDH1A1 | |
| SCHEMBL15459809 | 0.82 | USP2 (0.40) | USP2SMN1; SMN2NR1H2MEN1ALDH1A1 | |
| SCHEMBL733741 | 0.81 | USP2 (0.44) | USP2SMN1; SMN2NR1H2MEN1ALDH1A1 | |
| SCHEMBL734925 | 0.81 | USP2 (0.44) | USP2SMN1; SMN2NR1H2MEN1ALDH1A1 | |
| SCHEMBL9942499 | 0.81 | USP2 (0.44) | USP2SMN1; SMN2NR1H2MEN1ALDH1A1 | |
| SCHEMBL18204198 | 0.81 | CYP2D6 (0.49) | USP2ALDH1A1GPR119NAMPT | |
| SCHEMBL31511591 | 0.80 | GPR119 (0.40) | USP2SMN1; SMN2NR1H2MEN1ALDH1A1 | |
| SCHEMBL22004731 | 0.79 | EPHX2 (0.40) | USP2SMN1; SMN2NR1H2MEN1ALDH1A1 | |
| SCHEMBL31511552 | 0.79 | GPR119 (0.39) | USP2SMN1; SMN2NR1H2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024083208-A1 | KIF18A PROTEIN INHIBITOR | 杭州邦顺制药有限公司 | 2024-04-25 | — | — | WO | disclosed |
| CN-117917405-A | KIF18A protein inhibitors | 杭州邦顺制药有限公司 | 2024-04-23 | — | — | CN | disclosed |