Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | CLK3 | P49761 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17221743 | 1.00 | GBA1 (0.37) | GBA1MCHR1AKR1C3NPC1ALDH1A1 | |
| SCHEMBL24707519 | 0.90 | GBA1 (0.39) | GBA1AKR1C3NPC1ALDH1A1RAB9A | |
| SCHEMBL17221642 | 0.79 | MCHR1 (0.32) | MCHR1CYP1A2CYP2C9CYP2C19GRIN1 | |
| SCHEMBL17221791 | 0.79 | CSF1R (0.38) | MCHR1CNR2 | |
| SCHEMBL22899923 | 0.77 | ALDH1A1 (0.36) | GBA1AKR1C3NPC1ALDH1A1RAB9A | |
| SCHEMBL30934798 | 0.77 | ALDH1A1 (0.36) | GBA1AKR1C3NPC1ALDH1A1RAB9A | |
| SCHEMBL1928108 | 0.76 | MCHR1 (0.42) | MCHR1XDH | |
| SCHEMBL20465100 | 0.75 | DDB1 (0.32) | GBA1TSHR | |
| SCHEMBL3051022 | 0.74 | SLC6A4 (0.46) | GBA1 | |
| SCHEMBL17221789 | 0.73 | MAPK1 (0.44) | NPC1RAB9ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813302-A | Substituted tetrahydrofuran-2-carboxamides as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2024-04-02 | — | — | CN | disclosed |