⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3090116 | 0.89 | — | — | |
| SCHEMBL3065258 | 0.84 | TK1 (0.43) | — | |
| SCHEMBL3071137 | 0.84 | TK1 (0.43) | — | |
| SCHEMBL3066249 | 0.84 | TK1 (0.51) | — | |
| SCHEMBL3085750 | 0.82 | TK1 (0.60) | — | |
| SCHEMBL3085753 | 0.82 | TK1 (0.60) | — | |
| SCHEMBL3085563 | 0.80 | TK1 (0.40) | — | |
| SCHEMBL3078009 | 0.79 | TK2 (0.55) | — | |
| SCHEMBL3082887 | 0.79 | TK2 (0.46) | — | |
| SCHEMBL17135532 | 0.78 | TK1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054406-B1 | NUCLEOSIDES FOR SUPPRESSING OR REDUCING THE DEVELOPMENT OF RESISTANCE IN CYTOSTATIC THERAPY | RESPROTECT GMBH (DE) | 2015-10-07 | — | — | EP | disclosed |
| US-8492537-B2 | Nucleosides for suppressing or reducing the development of resistance in cytostatic therapy | RESPROTECT GMBH (DE) | 2013-07-23 | — | — | US | disclosed |
| US-20100227834-A1 | NUCLEOSIDES FOR SUPPRESSING OR REDUCING THE DEVELOPMENT OF RESISTANCE IN CYTOSTATIC THERAPY | RESprotech GmbH (DE) | 2010-09-09 | — | — | US | disclosed |