SCHEMBL30857433

SCHEMBL30857433

CC1(C(=O)N2CCC(c3cccnc3C(F)(F)F)CC2)COC1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 1/20 0.44
RBP4 P02753 9/20 0.42
IDO1 P14902 1/20 0.41
TDO2 P48775 1/20 0.41
BTK Q06187 1/20 0.40
TLR9 Q9NR96 2/20 0.40
TLR8 Q9NR97 2/20 0.40
TLR7 Q9NYK1 1/20 0.40
TRPV1 Q8NER1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30856724 0.87 RBP4 (0.43) RBP4IDO1TDO2TRPV1
SCHEMBL27196762 0.87 RBP4 (0.43) RBP4IDO1TDO2TRPV1
SCHEMBL30856723 0.85 RBP4 (0.41) RBP4IDO1TDO2TRPV1
SCHEMBL30856720 0.84 RBP4 (0.40) RBP4IDO1TDO2TRPV1
SCHEMBL27196773 0.84 RBP4 (0.40) RBP4IDO1TDO2TRPV1
SCHEMBL29598313 0.81 RBP4 (0.63) RBP4
SCHEMBL17505284 0.81 RBP4 (0.63) RBP4
SCHEMBL30857471 0.78 RBP4 (0.54) NAMPTRBP4
SCHEMBL29961897 0.75 SSTR4 (0.42) RBP4
SCHEMBL20744282 0.75 RBP4 (0.48) RBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382282-A1 NITROGEN-CONTAINING SATURATED HETEROCYCLYL DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2025-12-18 US disclosed
US-12172987-B2 Nitrogen-containing saturated heterocyclyl derivative Sumitomo Pharma Co., Ltd. (JP) 2024-12-24 US disclosed
US-20240124429-A1 NITROGEN-CONTAINING SATURATED HETEROCYCLYL DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2024-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382282-A1 NITROGEN-CONTAINING SATURATED HETEROCYCLYL DERIVATIVE H1-0, HTT, PRNP NAMPT 3599/4885RBP4 3913/4885IDO1 2884/4885
US-12172987-B2 Nitrogen-containing saturated heterocyclyl derivative H1-0, HTT, PRNP NAMPT 3599/4885RBP4 3913/4885IDO1 2884/4885
US-20240124429-A1 NITROGEN-CONTAINING SATURATED HETEROCYCLYL DERIVATIVE H1-0, HTT, PRNP NAMPT 3599/4885RBP4 3913/4885IDO1 2884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.