Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.72 |
| ▸ | HTR2C | P28335 | 11/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2507969 | 0.83 | HSD17B10 (0.93) | HSD17B10ALOX15L3MBTL1ALDH1A1GAA | |
| SCHEMBL29114224 | 0.80 | HSD17B10 (0.69) | HSD17B10ALOX15HTR2CL3MBTL1ALDH1A1 | |
| SCHEMBL11453712 | 0.79 | HTR2C (0.65) | HSD17B10ALOX15HTR2CALDH1A1HTR2A | |
| SCHEMBL11445688 | 0.78 | HTR2C (0.71) | HTR2CALDH1A1HTR2ACYP1A2CYP3A4 | |
| SCHEMBL29114225 | 0.78 | ALOX15 (0.60) | HSD17B10ALOX15HTR2CL3MBTL1ALDH1A1 | |
| SCHEMBL29114173 | 0.77 | HTR2C (0.60) | HSD17B10ALOX15HTR2CL3MBTL1ALDH1A1 | |
| SCHEMBL11455825 | 0.77 | HTR2C (0.81) | HTR2CALDH1A1HTR2ACYP1A2CYP3A4 | |
| SCHEMBL11481472 | 0.77 | HTR2C (0.65) | HTR2CALDH1A1HTR2ACYP1A2CYP3A4 | |
| SCHEMBL29114176 | 0.76 | HSD17B10 (0.66) | HSD17B10ALOX15HTR2CL3MBTL1ALDH1A1 | |
| SCHEMBL11447027 | 0.75 | HTR2C (0.57) | HSD17B10ALOX15HTR2CL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024067818-A1 | CHIMERIC COMPOUND USED FOR TARGETED DEGRADATION OF BCL-2 PROTEIN, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 江苏恒瑞医药股份有限公司 | 2024-04-04 | — | — | WO | disclosed |