Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30857796 | 1.00 | ESR2 (0.49) | ESR2ADORA1NR1H2USP2SMN1; SMN2 | |
| SCHEMBL30897992 | 0.90 | USP2 (0.50) | ESR2ADORA1NR1H2USP2SMN1; SMN2 | |
| SCHEMBL13291999 | 0.85 | ESR2 (0.50) | ESR2ADORA1NR1H2USP2SMN1; SMN2 | |
| SCHEMBL20007623 | 0.85 | ESR2 (0.50) | ESR2ADORA1NR1H2USP2SMN1; SMN2 | |
| SCHEMBL22488309 | 0.84 | ESR2 (0.47) | ESR2ADORA1NR1H2USP2SMN1; SMN2 | |
| SCHEMBL28687778 | 0.84 | ESR2 (0.49) | ESR2ADORA1NR1H2USP2SMN1; SMN2 | |
| SCHEMBL28693960 | 0.84 | ESR2 (0.49) | ESR2ADORA1NR1H2USP2SMN1; SMN2 | |
| SCHEMBL4279527 | 0.83 | ADORA1 (0.50) | ESR2ADORA1NR1H2USP2SMN1; SMN2 | |
| SCHEMBL4279524 | 0.83 | ADORA1 (0.50) | ESR2ADORA1NR1H2USP2SMN1; SMN2 | |
| SCHEMBL13028054 | 0.81 | ESR2 (0.47) | ESR2ADORA1NR1H2USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4563580-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND MEDICINAL APPLICATION THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2025-06-04 | — | — | EP | disclosed |
| CN-119365465-A | Condensed ring compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2025-01-24 | — | — | CN | disclosed |
| WO-2024022444-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND MEDICINAL APPLICATION THEREOF | 江苏恒瑞医药股份有限公司 | 2024-02-01 | — | — | WO | disclosed |