Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 8/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2290995 | 0.83 | GRM5 (0.44) | GRM5MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL31558715 | 0.81 | GRM5 (0.43) | GRM5CYP2C9TSHR | |
| SCHEMBL31558721 | 0.81 | NAMPT (0.44) | GRM5MAPT | |
| SCHEMBL31558713 | 0.80 | AKR1C3 (0.50) | AKR1C3MEN1TP53KMT2ALMNA | |
| SCHEMBL31558719 | 0.80 | AKR1C3 (0.50) | AKR1C3MEN1TP53KMT2ALMNA | |
| SCHEMBL31558707 | 0.80 | GRM5 (0.42) | GRM5 | |
| SCHEMBL31558712 | 0.78 | GRM5 (0.40) | GRM5MEN1KMT2A | |
| SCHEMBL31558699 | 0.76 | NAMPT (0.39) | GRM5 | |
| SCHEMBL31558705 | 0.76 | NAMPT (0.39) | GRM5 | |
| SCHEMBL31558697 | 0.75 | GRM5 (0.39) | GRM5MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119816496-A | Aromatic acetylene derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-04-11 | — | — | CN | disclosed |
| WO-2024067812-A1 | AROMATIC ACETYLENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2024-04-04 | — | — | WO | disclosed |