Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.54 |
| ▸ | SNCA | P37840 | 5/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30858755 | 1.00 | BCHE (0.54) | BCHESNCAACHEHPGDBACE1 | |
| SCHEMBL31022783 | 0.91 | BCHE (0.64) | BCHEBACE1MAPTMEN1ALOX12 | |
| SCHEMBL12813131 | 0.91 | BCHE (0.64) | BCHEBACE1MAPTMEN1ALOX12 | |
| SCHEMBL29406451 | 0.85 | SNCA (0.60) | BCHESNCAACHEHPGDTP53 | |
| SCHEMBL19918106 | 0.85 | SNCA (0.60) | BCHESNCAACHEHPGDTP53 | |
| SCHEMBL31425263 | 0.81 | BCHE (0.53) | BCHESNCAACHEHPGDTP53 | |
| SCHEMBL19918109 | 0.81 | SNCA (0.73) | BCHESNCAKDM4EMAPK1MAPT | |
| SCHEMBL29406423 | 0.81 | SNCA (0.73) | BCHESNCAKDM4EMAPK1MAPT | |
| SCHEMBL19942820 | 0.81 | BCHE (0.49) | BCHESNCAACHEHPGDTP53 | |
| SCHEMBL19939646 | 0.79 | BCHE (0.47) | BCHESNCAHPGDTP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050513-A1 | PHENOTHIAZINES FOR TREATING MITOCHONDRIAL DISEASE | ACUREX BIOSCIENCES CORPORATION (US) | 2024-03-07 | — | — | WO | disclosed |