SCHEMBL31022783

SCHEMBL31022783

CC(C)(C)OC(=O)N1c2ccc(Br)cc2Sc2cc(Br)ccc21

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ BCHE P06276 13/20 0.64
▸ NOX1 Q9Y5S8 1/20 0.42
▸ MEN1 O00255 1/20 0.40
▸ MAPT P10636 1/20 0.40
▸ ALOX12 P18054 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ CTDSP1 Q9GZU7 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ SLC6A3 Q01959 1/20 0.40
▸ CDK1 P06493 1/20 0.39
▸ BACE1 P56817 2/20 0.38
▸ USP30 Q70CQ3 1/20 0.37
▸ RBP4 P02753 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12813131 1.00 BCHE (0.64) BCHENOX1MEN1MAPTALOX12
SCHEMBL30858752 0.91 BCHE (0.54) BCHEMEN1MAPTALOX12KMT2A
SCHEMBL30858755 0.91 BCHE (0.54) BCHEMEN1MAPTALOX12KMT2A
SCHEMBL12273366 0.86 BCHE (0.49) BCHENOX1MEN1MAPTALOX12
SCHEMBL2591986 0.84 BCHE (0.47) BCHENOX1MEN1MAPTALOX12
SCHEMBL15908923 0.83 BCHE (0.46) BCHENOX1SMN1; SMN2SLC6A3CDK1
SCHEMBL14058478 0.82 BCHE (0.64) BCHENOX1MEN1MAPTALOX12
SCHEMBL12273405 0.81 BCHE (0.44) BCHENOX1MEN1KMT2ATDP1
SCHEMBL10083549 0.80 BCHE (0.61) BCHEMEN1KMT2ATDP1
SCHEMBL14142982 0.80 BCHE (0.61) BCHENOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651874-A2 PHENOTHIAZINYL COMPOUNDS AND USES Prosetta Biosciences, Inc. (US) 2025-11-26 — — EP disclosed
US-20240300940-A1 Phenothiazinyl Compounds and Uses PROSETTA BIOSCIENCES, INC., 2024-09-12 — — US disclosed
WO-2024178120-A2 PHENOTHIAZINYL COMPOUNDS AND USES PROSETTA BIOSCIENCES, INC. (US) 2024-08-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240300940-A1 Phenothiazinyl Compounds and Uses PSEN1, ACE, APP BCHE 21/4885NOX1 577/4885MEN1 1162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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