SCHEMBL30858765

SCHEMBL30858765

Cc1cc(O)cc(Oc2cc(C)cc(OCc3ccccc3Br)c2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.45
FFAR4 Q5NUL3 2/20 0.42
FFAR1 O14842 1/20 0.42
ANO1 Q5XXA6 2/20 0.41
MAOB P27338 2/20 0.40
ALDH1A1 P00352 3/20 0.40
IDO1 P14902 2/20 0.39
POLB P06746 1/20 0.38
MIF P14174 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
NPC1 O15118 2/20 0.38
MAPT P10636 2/20 0.38
RAB9A P51151 2/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PTPN1 P18031 1/20 0.38
F2 P00734 1/20 0.37
CA12 O43570 1/20 0.37
CA9 Q16790 1/20 0.37
AR P10275 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29261480 1.00 PARP10 (0.45) PARP10FFAR4FFAR1ANO1MAOB
SCHEMBL30858768 0.83 MAOB (0.48) FFAR4FFAR1MAOBNPC1MAPT
SCHEMBL29261483 0.83 MAOB (0.48) FFAR4FFAR1MAOBNPC1MAPT
SCHEMBL13678515 0.79 MAOB (0.53) FFAR1MAOBSMN1; SMN2
SCHEMBL30858764 0.77 MAOB (0.50) FFAR4FFAR1MAOBALDH1A1NPC1
SCHEMBL29261481 0.77 MAOB (0.50) FFAR4FFAR1MAOBALDH1A1NPC1
SCHEMBL30858763 0.77 MAOB (0.56) PARP10FFAR4FFAR1MAOB
SCHEMBL29261479 0.77 MAOB (0.56) PARP10FFAR4FFAR1MAOB
SCHEMBL6553403 0.77 MAOB (0.52) FFAR4FFAR1MAOBIDO1NPC1
SCHEMBL2290158 0.76 MAOB (0.54) PARP10FFAR4FFAR1ANO1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117945867-A Antibacterial active benzyl phenyl ether derivative and preparation method thereof 海南师范大学 2024-04-30 CN disclosed