SCHEMBL2290158

SCHEMBL2290158

Cc1cccc(OCc2ccccc2Br)c1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.54
PARP10 Q53GL7 1/20 0.48
MAPT P10636 2/20 0.46
ALDH1A1 P00352 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
IDO1 P14902 2/20 0.46
TP53 P04637 1/20 0.46
POLB P06746 1/20 0.46
ANO1 Q5XXA6 1/20 0.46
DRD2 P14416 1/20 0.45
DRD4 P21917 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
FFAR1 O14842 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
ACHE P22303 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1548999 0.88 MAOB (0.54) MAOBMAPTALDH1A1TDP1TP53
SCHEMBL12183099 0.83 CCNB2 (0.58) MAOBMAPTALDH1A1TDP1TP53
SCHEMBL13794364 0.83 MAOB (0.50) MAOBMAPTTDP1TP53POLB
SCHEMBL2291386 0.81 PARP10 (0.59) MAOBPARP10MAPTALDH1A1IDO1
SCHEMBL2287384 0.81 SOD1 (0.54) MAOBPARP10ALDH1A1TDP1IDO1
SCHEMBL25128164 0.80 ALDH1A1 (0.54) MAOBMAPTALDH1A1TDP1TP53
SCHEMBL257758 0.80 NR4A2 (0.60) MAOBMAPTIDO1TP53POLB
SCHEMBL21084234 0.80 LMNA (0.57) MAOBPARP10MAPTTDP1RAB9A
SCHEMBL8622258 0.80 MAOB (0.47) MAOBMAPTALDH1A1TP53POLB
SCHEMBL4639885 0.80 MAOB (0.60) MAOBPARP10MAPTALDH1A1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2149545-B1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2016-10-05 EP disclosed
US-7994367-B2 Method for producing benzaldehyde compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-09 US disclosed
US-20100210879-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-19 US disclosed
EP-2149545-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2010-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100210879-A1 METHOD FOR PRODUCING BENZALDEHYDE COMPOUND NQO1, C9, TRPA1 MAOB 272/4885PARP10 167/4885MAPT 3284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.