Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.65 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30858826 | 0.82 | HDAC1 (0.81) | HDAC1HDAC2HDAC6HDAC4HDAC3 | |
| SCHEMBL20509078 | 0.82 | HDAC1 (0.76) | HDAC1HDAC2HDAC6HDAC4HDAC3 | |
| SCHEMBL240482 | 0.80 | TRPV1 (0.61) | HDAC1HDAC2HDAC6HDAC4HDAC3 | |
| SCHEMBL30444576 | 0.80 | HDAC1 (0.81) | HDAC1HDAC2HDAC6HDAC4HDAC3 | |
| SCHEMBL15477455 | 0.80 | HDAC1 (0.81) | HDAC1HDAC2HDAC6HDAC4HDAC3 | |
| SCHEMBL5578205 | 0.79 | HDAC1 (1.00) | HDAC1HDAC2HDAC6HDAC4HDAC3 | |
| SCHEMBL4929814 | 0.79 | HDAC1 (0.71) | HDAC1HDAC2HDAC6HDAC4HDAC3 | |
| SCHEMBL30207564 | 0.79 | HPGD (0.57) | HDAC1HDAC2HDAC6HDAC4HDAC3 | |
| SCHEMBL29221845 | 0.78 | HDAC6 (0.73) | HDAC1HDAC2HDAC6HDAC4HDAC3 | |
| SCHEMBL30858828 | 0.78 | HDAC6 (0.73) | HDAC1HDAC2HDAC6HDAC4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886748-A | Quinoline amino acid conjugate and preparation method and application thereof | 天津科技大学 | 2024-04-16 | — | — | CN | disclosed |