Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 18/20 | 0.72 |
| ▸ | FLT4 | P35916 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | FLT3 | P36888 | 2/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25564587 | 1.00 | CSF1R (0.72) | CSF1RFLT4KDRFLT3KIT | |
| SCHEMBL29213103 | 1.00 | CSF1R (0.72) | CSF1RFLT4KDRFLT3KIT | |
| SCHEMBL29213100 | 0.86 | CSF1R (0.79) | CSF1R | |
| SCHEMBL25564654 | 0.86 | CSF1R (0.79) | CSF1R | |
| SCHEMBL25264341 | 0.85 | CSF1R (0.54) | CSF1RKDRFLT3 | |
| SCHEMBL25181652 | 0.85 | CSF1R (0.54) | CSF1RKDRFLT3 | |
| SCHEMBL30860263 | 0.84 | CSF1R (1.00) | CSF1R | |
| SCHEMBL25564495 | 0.84 | CSF1R (1.00) | CSF1R | |
| SCHEMBL29213102 | 0.84 | CSF1R (1.00) | CSF1R | |
| SCHEMBL3611724 | 0.76 | NTRK1 (0.54) | CSF1RFLT4KDRFLT3KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999221-B | 6-substituted indolone derivative and medical application thereof | 南京中医药大学 | 2024-04-05 | — | — | CN | disclosed |