SCHEMBL30860263

SCHEMBL30860263

CC(C)(C)c1cc(NC(=O)Nc2ccc3c(c2)NC(=O)/C3=C\c2cnc[nH]2)on1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CSF1R P07333 19/20 1.00
▸ TLK2 Q86UE8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29213102 1.00 CSF1R (1.00) CSF1RTLK2
SCHEMBL25564495 1.00 CSF1R (1.00) CSF1RTLK2
SCHEMBL25564615 0.85 CSF1R (1.00) CSF1R
SCHEMBL29213101 0.85 CSF1R (1.00) CSF1R
SCHEMBL25177522 0.85 CSF1R (0.75) CSF1RTLK2
SCHEMBL25184575 0.85 CSF1R (1.00) CSF1RTLK2
SCHEMBL25184579 0.85 CSF1R (1.00) CSF1RTLK2
SCHEMBL29213103 0.84 CSF1R (0.72) CSF1R
SCHEMBL30860221 0.84 CSF1R (0.72) CSF1R
SCHEMBL25564587 0.84 CSF1R (0.72) CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113999221-B 6-substituted indolone derivative and medical application thereof 南京中医药大学 2024-04-05 — — CN disclosed
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