Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.44 |
| ▸ | INSR | P06213 | 2/20 | 0.44 |
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30860328 | 0.97 | EGFR (0.50) | EGFRALKINSRIGF1RMET | |
| SCHEMBL30860260 | 0.96 | EGFR (0.54) | EGFRALKINSRIGF1RMET | |
| SCHEMBL26906557 | 0.96 | EGFR (0.53) | EGFRALKINSRIGF1RMET | |
| SCHEMBL26906604 | 0.95 | EGFR (0.53) | EGFRALKINSRIGF1RMET | |
| SCHEMBL30860318 | 0.93 | EGFR (0.52) | EGFRALKINSRIGF1RMET | |
| SCHEMBL30860404 | 0.93 | EGFR (0.51) | EGFRALKINSRIGF1R | |
| SCHEMBL26906861 | 0.91 | EGFR (0.56) | EGFRALKINSRIGF1RMET | |
| SCHEMBL29114963 | 0.90 | EGFR (0.59) | EGFRALKINSRIGF1RMET | |
| SCHEMBL30860293 | 0.90 | EGFR (0.60) | EGFRALKINSRIGF1RMET | |
| SCHEMBL26906904 | 0.90 | EGFR (0.60) | EGFRALKINSRIGF1RMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | claimed |
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | disclosed |