Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.58 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30860340 | 0.93 | EGFR (0.56) | EGFRBTK | |
| SCHEMBL27091519 | 0.90 | EGFR (0.67) | EGFRBTK | |
| SCHEMBL30860424 | 0.90 | EGFR (0.56) | EGFRBTKPLK1 | |
| SCHEMBL30860448 | 0.89 | EGFR (0.62) | EGFRBTK | |
| SCHEMBL30860270 | 0.88 | EGFR (0.58) | EGFR | |
| SCHEMBL30860759 | 0.86 | EGFR (0.56) | EGFRBTK | |
| SCHEMBL27091391 | 0.85 | EGFR (0.75) | EGFRBTK | |
| SCHEMBL29785248 | 0.85 | EGFR (0.63) | EGFR | |
| SCHEMBL27091514 | 0.85 | EGFR (0.63) | EGFR | |
| SCHEMBL29084096 | 0.84 | EGFR (0.71) | EGFRBTKPLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | claimed |
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | disclosed |