Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30860331 | 0.96 | EGFR (0.47) | EGFR | |
| SCHEMBL26906936 | 0.95 | EGFR (0.56) | EGFRALK | |
| SCHEMBL26906665 | 0.91 | EGFR (0.53) | EGFR | |
| SCHEMBL30860358 | 0.91 | EGFR (0.49) | EGFRALK | |
| SCHEMBL30860387 | 0.90 | EGFR (0.47) | EGFRALK | |
| SCHEMBL26906596 | 0.90 | EGFR (0.55) | EGFR | |
| SCHEMBL26906557 | 0.90 | EGFR (0.53) | EGFRALK | |
| SCHEMBL26906882 | 0.89 | EGFR (0.49) | EGFRALK | |
| SCHEMBL30860404 | 0.87 | EGFR (0.51) | EGFRALK | |
| SCHEMBL26906670 | 0.87 | EGFR (0.66) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | claimed |
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | disclosed |