Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26906966 | 0.95 | EGFR (0.46) | EGFRALK | |
| SCHEMBL30860331 | 0.94 | EGFR (0.47) | EGFRMET | |
| SCHEMBL26906748 | 0.94 | EGFR (0.52) | EGFRMETZAP70LRRK2 | |
| SCHEMBL26906882 | 0.91 | EGFR (0.49) | EGFRALK | |
| SCHEMBL30860332 | 0.90 | EGFR (0.49) | EGFRALK | |
| SCHEMBL26906665 | 0.90 | EGFR (0.53) | EGFRMET | |
| SCHEMBL26906576 | 0.89 | EGFR (0.54) | EGFRALK | |
| SCHEMBL30659887 | 0.88 | EGFR (0.51) | EGFRLRRK2 | |
| SCHEMBL26906679 | 0.88 | EGFR (0.51) | EGFRLRRK2 | |
| SCHEMBL26906596 | 0.88 | EGFR (0.55) | EGFRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | claimed |
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | disclosed |