Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.54 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30860333 | 0.90 | EGFR (0.59) | EGFRMETALKINSRIGF1R | |
| SCHEMBL25001448 | 0.90 | EGFR (0.58) | EGFRMETPLK1ALKINSR | |
| SCHEMBL30860353 | 0.89 | EGFR (0.56) | EGFRMETPLK1ALKINSR | |
| SCHEMBL30860424 | 0.88 | EGFR (0.56) | EGFRMETPLK1ALKINSR | |
| SCHEMBL30860759 | 0.88 | EGFR (0.56) | EGFRMET | |
| SCHEMBL30860746 | 0.87 | EGFR (0.54) | EGFRMETPLK1 | |
| SCHEMBL29785229 | 0.84 | EGFR (0.62) | EGFR | |
| SCHEMBL27091359 | 0.84 | EGFR (0.62) | EGFR | |
| SCHEMBL25001347 | 0.82 | EGFR (0.63) | EGFRMETPLK1ALKINSR | |
| SCHEMBL30860750 | 0.82 | EGFR (0.55) | EGFRMETPLK1ALKINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | claimed |
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | disclosed |