Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 18/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.49 |
| ▸ | ULK1 | O75385 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27228045 | 1.00 | LRRK2 (0.51) | LRRK2CYP1A2ULK1 | |
| SCHEMBL27227971 | 0.88 | LRRK2 (0.53) | LRRK2CYP1A2ULK1 | |
| SCHEMBL30860843 | 0.88 | LRRK2 (0.52) | LRRK2CYP1A2ULK1 | |
| SCHEMBL30861027 | 0.88 | LRRK2 (0.53) | LRRK2CYP1A2ULK1 | |
| SCHEMBL27227903 | 0.88 | LRRK2 (0.52) | LRRK2CYP1A2ULK1 | |
| SCHEMBL27228523 | 0.85 | LRRK2 (0.62) | LRRK2 | |
| SCHEMBL30861094 | 0.85 | LRRK2 (0.62) | LRRK2 | |
| SCHEMBL30860864 | 0.80 | ULK1 (0.57) | LRRK2CYP1A2ULK1 | |
| SCHEMBL30860933 | 0.80 | LRRK2 (0.54) | LRRK2CYP1A2ULK1 | |
| SCHEMBL27228375 | 0.80 | ULK1 (0.57) | LRRK2CYP1A2ULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073073-A2 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-04-04 | — | — | WO | disclosed |