Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 6/20 | 0.59 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.59 |
| ▸ | ULK1 | O75385 | 9/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.54 |
| ▸ | ULK2 | Q8IYT8 | 2/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27228222 | 1.00 | FLT3 (0.59) | FLT3CHEK1ULK1LRRK2ULK2 | |
| SCHEMBL27227990 | 0.90 | LRRK2 (0.56) | FLT3CHEK1ULK1LRRK2ULK2 | |
| SCHEMBL30860772 | 0.90 | LRRK2 (0.56) | FLT3CHEK1ULK1LRRK2ULK2 | |
| SCHEMBL30860992 | 0.89 | ULK1 (0.58) | FLT3CHEK1ULK1LRRK2ULK2 | |
| SCHEMBL27227885 | 0.89 | ULK1 (0.58) | FLT3CHEK1ULK1LRRK2ULK2 | |
| SCHEMBL30861098 | 0.88 | LRRK2 (0.69) | ULK1LRRK2 | |
| SCHEMBL27227808 | 0.88 | LRRK2 (0.69) | ULK1LRRK2 | |
| SCHEMBL30861055 | 0.88 | FLT3 (0.46) | FLT3CHEK1ULK1LRRK2 | |
| SCHEMBL30860987 | 0.88 | FLT3 (0.59) | FLT3CHEK1ULK1LRRK2ULK2 | |
| SCHEMBL27227799 | 0.88 | FLT3 (0.46) | FLT3CHEK1ULK1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073073-A2 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-04-04 | — | — | WO | disclosed |