Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 4/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3081309 | 0.79 | BTK (0.38) | BTKALOX5DDB1CRBNNFE2L2 | |
| SCHEMBL30460302 | 0.79 | PDE2A (0.48) | BTKALOX5DDB1CRBNNFE2L2 | |
| SCHEMBL29530386 | 0.79 | NQO1 (0.44) | BTK | |
| SCHEMBL874972 | 0.79 | NQO1 (0.44) | BTK | |
| SCHEMBL6161278 | 0.79 | PDE2A (0.48) | BTKALOX5DDB1CRBNNFE2L2 | |
| SCHEMBL23704126 | 0.78 | GRM5 (0.39) | BTKOGAKDM4EALDH1A1HPGD | |
| SCHEMBL465617 | 0.77 | CYP3A4 (0.33) | TDP1KDM4EALDH1A1HPGD | |
| SCHEMBL160602 | 0.77 | BTK (0.47) | BTKALOX5DDB1CRBNPOLB | |
| SCHEMBL4155842 | 0.76 | GRM5 (0.38) | BTKOGAKDM4EALDH1A1HPGD | |
| SCHEMBL4160556 | 0.73 | OGA (0.40) | POLBTDP1OGAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018227427-A1 | SUBSTITUTED BRIDGED DIAZEPANE DERIVATIVES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-12-20 | — | — | WO | disclosed |
| US-20100233415-A1 | OPTICAL RECORDING MEDIUM AND AZO METAL CHELATE COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-1997856-A1 | OPTICAL RECORDING MEDIUM AND AZO METAL CHELATE COMPOUND | Mitsui Chemicals, Inc. (JP) | 2008-12-03 | — | — | EP | disclosed |