Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PDE9A | O76083 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17372835 | 1.00 | CLK1 (0.35) | CLK1DYRK1AMAOAMAOBPDE9A | |
| SCHEMBL24203201 | 0.73 | KDM4E (0.35) | KDM4EMAPTKMT2AGRIN2DGRIN3B | |
| SCHEMBL22916478 | 0.67 | MEN1 (0.36) | KDM4EMAPTKMT2AGRIN2DGRIN3B | |
| SCHEMBL22361318 | 0.64 | PDE9A (0.32) | PDE9AKDM4EMAPTKMT2AGRIN2D | |
| SCHEMBL10743051 | 0.64 | AHR (0.56) | KDM4EMAPTKMT2AGRIN2DGRIN3B | |
| SCHEMBL29385786 | 0.64 | AHR (0.56) | KDM4EMAPTKMT2AGRIN2DGRIN3B | |
| SCHEMBL21433663 | 0.63 | ITK (0.49) | KMT2AMEN1CA1CA2CYP19A1 | |
| SCHEMBL29528180 | 0.63 | ITK (0.49) | KMT2AMEN1CA1CA2CYP19A1 | |
| SCHEMBL22773797 | 0.63 | CHUK (0.54) | KMT2AMEN1L3MBTL1FASNCA1 | |
| SCHEMBL19731074 | 0.62 | AHR (0.61) | KDM4EMAPTKMT2AGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417858-B | Intracellular self-assembled ALK degradation agent based on bioorthogonal strategy and preparation method and application thereof | 中国药科大学 | 2024-04-19 | — | — | CN | disclosed |