SCHEMBL24203201

SCHEMBL24203201

C1=Cc2[nH]c3cc4ccccc4cc3c2CC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.35
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2B Q13224 1/20 0.35
GRIN2C Q14957 1/20 0.35
GRIN3A Q8TCU5 1/20 0.35
PDE3B Q13370 1/20 0.35
PDE3A Q14432 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CHEK1 O14757 1/20 0.32
NPC1 O15118 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23839460 0.84 HTR2A (0.34) KDM4EMAPTMEN1KMT2ANPC1
SCHEMBL16977068 0.81 AHR (0.55) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL24727761 0.80 FEN1 (0.43) KDM4EMAPTMEN1KMT2ACHEK1
SCHEMBL23894629 0.80 AHR (0.49) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL2307927 0.80 HTR2A (0.43) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL17146447 0.78 AHR (0.42) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL17563212 0.76 GSK3A (0.45) NPC1
SCHEMBL808411 0.75 RAB9A (0.35) KDM4EMAPTL3MBTL1NPC1ALDH1A1
SCHEMBL22316850 0.75 KIF11 (0.35) KDM4EMAPTGRIN2DGRIN3BGRIN1
SCHEMBL21474736 0.74 KDM4E (0.35) KDM4EMAPTGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553049-B1 COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING SAME LG CHEMICAL LTD (KR) 2022-01-19 EP disclosed