Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29238197 | 1.00 | SRC (0.35) | SRCABL1PDE9ASMN1; SMN2HSP90AA1 | |
| SCHEMBL29238195 | 1.00 | SRC (0.35) | SRCABL1PDE9ASMN1; SMN2HSP90AA1 | |
| SCHEMBL29147605 | 0.79 | CYP4F2 (0.42) | SRCABL1PDE9ASMN1; SMN2HSP90AA1 | |
| SCHEMBL29147608 | 0.79 | CYP4F2 (0.42) | SRCABL1PDE9ASMN1; SMN2HSP90AA1 | |
| SCHEMBL30633933 | 0.79 | CYP4F2 (0.42) | SRCABL1PDE9ASMN1; SMN2HSP90AA1 | |
| SCHEMBL29238156 | 0.62 | — | — | |
| SCHEMBL29921383 | 0.62 | CYP4F2 (0.43) | PDE9ASMN1; SMN2LMNAGAA | |
| SCHEMBL28575619 | 0.62 | CYP4F2 (0.43) | PDE9ASMN1; SMN2LMNAGAA | |
| SCHEMBL26685088 | 0.56 | AHR (0.49) | SMN1; SMN2HSP90AA1MAPK1GAA | |
| SCHEMBL26685006 | 0.56 | AHR (0.49) | SMN1; SMN2HSP90AA1MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116964046-B | PLK4 inhibitors and uses thereof | 上海齐鲁制药研究中心有限公司 | 2024-04-19 | — | — | CN | disclosed |