Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 9/20 | 1.00 |
| ▸ | TDO2 | P48775 | 7/20 | 1.00 |
| ▸ | IDO2 | Q6ZQW0 | 7/20 | 1.00 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.69 |
| ▸ | PIM1 | P11309 | 1/20 | 0.69 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.69 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.69 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.69 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | APAF1 | O14727 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | MITF | O75030 | 1/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30239959 | 1.00 | IDO1 (1.00) | IDO1TDO2IDO2CHEK1PIM1 | |
| SCHEMBL4585619 | 1.00 | IDO1 (1.00) | IDO1TDO2IDO2CHEK1PIM1 | |
| SCHEMBL30639105 | 0.86 | IDO1 (0.75) | IDO1TDO2IDO2CHEK1PIM1 | |
| SCHEMBL26614103 | 0.86 | IDO1 (0.75) | IDO1TDO2IDO2CHEK1PIM1 | |
| SCHEMBL31382858 | 0.86 | IDO1 (0.75) | IDO1TDO2IDO2CHEK1PIM1 | |
| SCHEMBL26614196 | 0.86 | IDO1 (0.75) | IDO1TDO2IDO2CHEK1PIM1 | |
| SCHEMBL9113254 | 0.85 | TDO2 (0.74) | IDO1TDO2IDO2CHEK1PIM1 | |
| SCHEMBL31382836 | 0.85 | IDO1 (0.74) | IDO1TDO2IDO2CHEK1PIM1 | |
| SCHEMBL26614201 | 0.85 | IDO1 (0.74) | IDO1TDO2IDO2CHEK1PIM1 | |
| SCHEMBL31382839 | 0.85 | IDO1 (0.73) | IDO1TDO2IDO2CHEK1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659024-A | Amide substituted tryptanthrin derivative and preparation method and application thereof | 安徽医科大学 | 2024-03-08 | — | — | CN | claimed |
| CN-119487031-A | Tryptanthrin derivatives and uses thereof | 威森特生物公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-117659024-A | Amide substituted tryptanthrin derivative and preparation method and application thereof | 安徽医科大学 | 2024-03-08 | — | — | CN | disclosed |