SCHEMBL30863424

SCHEMBL30863424

COC(=O)c1ccc(NC(=O)c2ccc(C3CCN(C)CC3)cc2)c2ncccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC3 O15379 2/20 0.53
▸ HDAC1 Q13547 2/20 0.53
▸ HDAC2 Q92769 2/20 0.53
▸ HDAC4 P56524 1/20 0.53
▸ HDAC7 Q8WUI4 1/20 0.53
▸ HDAC10 Q969S8 1/20 0.53
▸ HDAC11 Q96DB2 1/20 0.53
▸ HDAC8 Q9BY41 1/20 0.53
▸ HDAC6 Q9UBN7 1/20 0.53
▸ HDAC9 Q9UKV0 1/20 0.53
▸ HDAC5 Q9UQL6 1/20 0.53
▸ KDM4E B2RXH2 2/20 0.49
▸ KDM1A O60341 2/20 0.45
▸ MAOA P21397 2/20 0.45
▸ KDM1B Q8NB78 2/20 0.45
▸ RCOR1 Q9UKL0 2/20 0.45
▸ FGFR1 P11362 3/20 0.42
▸ PDE4D Q08499 2/20 0.42
▸ KMT2A Q03164 3/20 0.41
▸ MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27195730 0.85 HDAC1 (0.58) HDAC3HDAC1HDAC2HDAC4HDAC7
Hydrochloric Acid SCHEMBL30863433 0.84 F10 (0.50) HDAC3HDAC8KDM4EKMT2AMEN1
SCHEMBL27195716 0.82 HDAC1 (0.55) HDAC3HDAC1HDAC2HDAC4HDAC7
SCHEMBL27195780 0.82 HDAC1 (0.58) HDAC3HDAC1HDAC2HDAC4HDAC7
SCHEMBL27195743 0.81 HDAC6 (0.62) HDAC3HDAC1HDAC2HDAC4HDAC7
SCHEMBL27195701 0.78 HDAC6 (0.61) HDAC3HDAC1HDAC2HDAC4HDAC7
SCHEMBL27195724 0.77 HDAC1 (0.62) HDAC3HDAC1HDAC2HDAC4HDAC7
SCHEMBL30863481 0.77 HDAC1 (0.59) HDAC3HDAC1HDAC2HDAC4HDAC7
SCHEMBL27195694 0.77 HDAC1 (0.59) HDAC3HDAC1HDAC2HDAC4HDAC7
SCHEMBL27195750 0.73 MEN1 (0.60) HDAC8KDM4EKMT2AMEN1HTR1F

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP claimed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP disclosed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO disclosed
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