SCHEMBL30863559

SCHEMBL30863559

COc1cc(NC(=O)c2ccc(N3CCN(C)CC3)cc2)c2cnccc2c1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 14/20 0.59
▸ NPC1 O15118 2/20 0.56
▸ RAB9A P51151 2/20 0.56
▸ FGFR1 P11362 2/20 0.53
▸ KDR P35968 2/20 0.53
▸ AURKA O14965 1/20 0.52
▸ TTK P33981 1/20 0.52
▸ AURKB Q96GD4 1/20 0.52
▸ INCENP Q9NQS7 1/20 0.52
▸ KLKB1 P03952 1/20 0.50
▸ POLB P06746 1/20 0.48
▸ FGFR2 P21802 1/20 0.48
▸ FGFR3 P22607 1/20 0.48
▸ HDAC3 O15379 1/20 0.48
▸ HDAC8 Q9BY41 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30863551 0.91 F10 (0.58) F10NPC1RAB9AFGFR1KDR
SCHEMBL30863513 0.86 AURKA (0.53) F10NPC1RAB9AFGFR1KDR
SCHEMBL30863451 0.85 HDAC3 (0.50) F10FGFR1FGFR3HDAC3HDAC8
SCHEMBL27195758 0.83 AURKA (0.53) F10NPC1RAB9AAURKATTK
Hydrochloric Acid SCHEMBL30863442 0.79 NPC1 (0.54) F10NPC1RAB9AAURKATTK
SCHEMBL30863527 0.77 HDAC3 (0.50) F10FGFR1FGFR3HDAC3HDAC8
SCHEMBL27195706 0.76 TRPV1 (0.58) F10NPC1RAB9AAURKATTK
SCHEMBL30863502 0.76 HDAC3 (0.59) F10NPC1RAB9AAURKATTK
SCHEMBL27195914 0.76 HDAC3 (0.59) F10NPC1RAB9AAURKATTK
Hydrochloric Acid SCHEMBL27195736 0.75 AURKA (0.52) F10NPC1RAB9AAURKATTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP claimed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP disclosed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO disclosed
Send feedback