SCHEMBL27195706

SCHEMBL27195706

CN1CCN(c2ccc(C(=O)Nc3cccc4cnccc34)cc2)CC1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TRPV1 Q8NER1 10/20 0.58
▸ CNR1 P21554 1/20 0.54
▸ AURKA O14965 1/20 0.53
▸ TTK P33981 1/20 0.53
▸ AURKB Q96GD4 1/20 0.53
▸ INCENP Q9NQS7 1/20 0.53
▸ F10 P00742 5/20 0.53
▸ NPC1 O15118 2/20 0.51
▸ RAB9A P51151 2/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ MAPK1 P28482 1/20 0.51
▸ HTT P42858 1/20 0.51
▸ BLM P54132 1/20 0.51
▸ KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27195758 0.91 AURKA (0.53) AURKATTKAURKBINCENPF10
SCHEMBL27195721 0.87 SIRT6 (0.55) TRPV1CNR1KMT2A
SCHEMBL27195688 0.84 TRPV1 (0.57) TRPV1CNR1MAPK1
SCHEMBL30863450 0.84 TRPV1 (0.57) TRPV1CNR1MAPK1
SCHEMBL27195713 0.83 HDAC6 (0.60) TRPV1CNR1MEN1MAPK1HTT
Hydrochloric Acid SCHEMBL30863551 0.82 F10 (0.58) AURKATTKAURKBINCENPF10
SCHEMBL27195914 0.82 HDAC3 (0.59) AURKATTKAURKBINCENPF10
SCHEMBL30863502 0.82 HDAC3 (0.59) AURKATTKAURKBINCENPF10
SCHEMBL30863515 0.81 TRPV1 (0.59) TRPV1
Hydrochloric Acid SCHEMBL27195736 0.81 AURKA (0.52) AURKATTKAURKBINCENPF10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP claimed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO claimed
EP-4353712-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2024-04-17 — — EP claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP disclosed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO disclosed
EP-4353712-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2024-04-17 — — EP disclosed
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